Abstract Clinical features honeywell pa404a1009 of sudden sensorineural hearing loss (SSNHL) associated with vestibular schwannoma (VS) are not fully understood.Determining a treatment plan and explaining it to patients requires clinicians to clearly understand the clinical features related to the tumor, including SSNHL.To identify the full range of clinical features of VS-associated SSNHL, especially recovery of hearing following multiple episodes of SSNHL and what factors predict recovery and recurrence.
A multicenter retrospective chart review was conducted in seven tertiary care hospitals between April 1, 2011, and March 31, 2020.We collected and analyzed dose of administered steroid, pure-tone audiometry results, and brain MRIs of patients diagnosed with VS-associated SSNHL.Seventy-seven patients were included.
They experienced 109 episodes of audiogram-confirmed SSNHL.The highest proportion of complete recoveries occurred in patients with U-shaped audiograms.The recovery rates for the first, second, and third and subsequent episodes of SSNHL were standoff kingsville ontario 53.
5%, 28.0%, and 9.1%, respectively.
Recovery rate decreased significantly with increasing number of SSNHL episodes (P =0.0011; Cochran-Armitage test).After the first episode of SSNHL, the recurrence-free rate was 69.
9% over 1 year and 57.7% over 2 years; the median recurrence time was 32 months.Logarithmic approximation revealed that there is a 25% probability that SSNHL would recur within a year.
SSNHL in patients with VS is likely to recur within one year in 25% of cases.Also, recovery rate decreases as a patient experiences increasing episodes of SSNHL.